Alcohol Use Disorders: Behavioral Treatment, Services and Recovery Research (R01 Clinical Trial Optional) | PA 18 194

Opportunity Information: Apply for PA 18 194

The National Institutes of Health (NIH) funding opportunity titled "Alcohol Use Disorders: Behavioral Treatment, Services and Recovery Research (R01 Clinical Trial Optional)" (Funding Opportunity Number PA-18-194; CFDA 93.273) is a discretionary grant program that uses the NIH R01 mechanism to support research focused on alcohol use disorders (AUD). The central aim is to fund rigorous, hypothesis-driven studies that improve understanding of how behavioral treatments work, how alcohol-related services are delivered in real-world settings, and what helps or hinders long-term recovery. A key feature of this announcement is that clinical trials are optional, meaning applicants may propose either clinical trial research or non-trial research, as long as the work directly advances knowledge about behavioral treatment, service delivery systems, or recovery processes for AUD.

The scope of the research encouraged by this announcement covers three closely connected areas. First, it supports research on behavioral treatments for AUD, which can include developing, refining, testing, and implementing psychosocial and behavioral interventions. This can involve examining treatment effectiveness, mechanisms of behavior change, strategies to improve engagement and retention, approaches tailored to different populations, and methods to integrate behavioral care with other health and social services. Second, it explicitly invites research on the organizational, financial, and management factors that shape the delivery of AUD services. In practice, this points to studies on how clinics, health systems, community programs, and other service settings adopt and sustain evidence-based practices; how staffing, training, workflow, leadership, reimbursement, and quality improvement systems affect what care is provided; and how policy and financing structures can either enable or obstruct access and continuity of care. Third, the FOA encourages research on recovery from alcohol use disorders as a phenomenon, which can include studies of recovery trajectories, recovery supports, and factors that promote sustained remission and improved functioning over time. This may include work that looks beyond symptom reduction to broader outcomes such as quality of life, housing stability, employment, social connection, and co-occurring health and mental health conditions, depending on the proposed study aims.

In terms of who can apply, the opportunity is broadly open to many types of organizations and governmental entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions when categorized separately); for-profit organizations other than small businesses; and small businesses. The announcement also highlights additional eligible applicant categories, signaling NIH interest in a wide range of community-rooted, mission-driven, and minority-serving institutions. These include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-domestic (non-U.S.) entities (foreign organizations). Taken together, this eligibility breadth is meant to encourage applications from diverse settings that can study AUD treatment and recovery across different communities and service systems.

Administratively, this is an NIH grant opportunity (Funding Instrument Type: Grant; Activity Category: Health) with an original closing date listed as September 7, 2018, and an original creation date of November 6, 2017. The provided source data does not specify an award ceiling or the expected number of awards, which often means budgets and award counts may vary depending on the scientific scope, proposed approach, and available funds in a given cycle, consistent with many NIH R01 announcements. Overall, the opportunity is designed to build practical, usable evidence about how to improve behavioral treatment outcomes for AUD, how to strengthen the systems that deliver AUD services, and how to better understand and support recovery in real-world contexts.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Alcohol Use Disorders: Behavioral Treatment, Services and Recovery Research (R01 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
• This funding opportunity was created on 2017-11-06.
• Applicants must submit their applications by 2018-09-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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