Opportunity Information: Apply for PAR 17 094

The Maximizing Investigators' Research Award (MIRA) (R35) is a National Institutes of Health (NIH) grant opportunity from the National Institute of General Medical Sciences (NIGMS) designed to support an investigator's overall research program rather than a single, tightly defined project. In this context, a "program of research" means the collection of related projects conducted in an investigator's laboratory that align with the NIGMS mission. The central idea is to provide more flexible, stable support so investigators can pursue cohesive lines of inquiry, adapt to new findings, and manage their labs more efficiently without having to constantly repackage work into multiple separate grant applications. Overall, the stated goal is to increase the efficiency and effectiveness of NIGMS funding by investing in investigators and their broader research directions.

This opportunity is a discretionary, health-focused grant mechanism (Funding Instrument: Grant; Activity Category: Health) under Funding Opportunity Number PAR 17 094, associated with CFDA number 93.859. The opportunity was created on 2016-12-21, and the original closing date listed for the competition was 2019-05-17. The listing does not provide an award ceiling or expected number of awards, which typically means applicants need to consult the full announcement and NIH policy details for budget expectations, award ranges, and how many awards might be made in a given cycle.

Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits both with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; small businesses; and other entities as allowed by NIH policy. The opportunity also highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, Indian/Native American Tribal Governments other than federally recognized entities, and U.S. territories or possessions.

Restrictions related to foreign participation are specific. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as applicant organizations, and non-domestic components of U.S. organizations are not eligible to apply. However, "foreign components" are allowed as defined in the NIH Grants Policy Statement, meaning a U.S. applicant may include certain elements of the work that take place outside the United States if they meet NIH's definition and requirements for a foreign component (for example, specialized resources, unique populations, or collaborations abroad that are justified and appropriately documented).

In practical terms, MIRA is meant for investigators whose labs run multiple interrelated projects within NIGMS-relevant areas and who would benefit from a single award supporting that integrated program. Instead of funding a narrowly scoped aim set, this mechanism emphasizes supporting the overall direction and productivity of the investigator's research enterprise, with the broader intent of reducing administrative burden, improving continuity of support, and enabling more responsive and innovative science within NIGMS's mission space.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Maximizing Investigators' Research Award (R35)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
  • This funding opportunity was created on 2016-12-21.
  • Applicants must submit their applications by 2019-05-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 17 094

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Strengthening the HIV Pre-Exposure Prophylaxis (PrEP) Care Continuum through Behavioral, Social, and Implementation Science (R01) Apply for PA 17 104

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Funding Number: PA 17 113
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Funding Number: PA 17 114
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Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R41/R42) Apply for PAR 17 107

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Development of Socially-Assistive Robots (SARs) to Engage Persons with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD), and their Caregivers (R43/R44) Apply for PAR 17 108

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Funding Number: PA 17 106
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Targeted basic behavioral and social science and intervention development for HIV prevention and care (R21) Apply for PA 17 105

Funding Number: PA 17 105
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NINDS Exploratory Clinical Trials (R01) Apply for PAR 17 122

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Funding Number: SBUR SOGAC 16 003
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Juvenile Protective Factors and Their Effects on Aging (R01) Apply for PAR 17 126

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Juvenile Protective Factors and Their Effects on Aging (R03) Apply for PAR 17 127

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